Newcastle United are set to make another attempt with Alexander Isak, with the Swedish striker expected to be called upon to prepare for next week's encounter at Elland Road.
Howe said on Friday that PIF would not permit the Magpies to enter the opening half of the new campaign without a senior striker, meaning Isak's desired switch to Liverpool will not be approved unless a replacement is secured before the transfer window closes.
Following Newcastle being informed of astronomical valuations for Wolves' Jorgen Strand Larsen and Chelsea's Nicolas Jackson, it appeared Howe was left with dwindling alternatives at the end of last week.
The Isak situation was put on hold as preparations for tonight's Liverpool fixture were intensified, but United are preparing for a second approach from the Reds before the window concludes.
Howe has not completely given up on Isak and intends to hold fresh talks with the Swedish international once the Liverpool match is concluded, reports Chronicle Live.
Whether Isak will be willing to rejoin the squad following his contentious decision to miss the club's Far East tour and opt to train independently in Spain last month remains uncertain.
The speculation circulating behind the scenes at St James' Park continues to suggest that Isak's only route to securing a transfer to Liverpool is for the Reds to table an offer of approximately £150m.
Speaking ahead of the Liverpool clash, Howe stated: "We are making decisions based on what we think is the best for Newcastle United.
"They are being strong on the valuations of players and on how a player leaves the football club, all of these things are important. They are important on this situation and also the future."
Isak released a strong post on Instagram last week making it clear that he wanted to leave Newcastle.
When discussing if PIF would make their own statement, Howe said: "I don't think they (PIF) are trying to make any overall big statement, but just reacting to this individual statement."
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